Zepteon: Separation of Nonfucosylated Antibodies

Zepteon, Inc. is a privately held corporation founded in 2012 that has developed a first in class chromatography resin, Glycap-3A, capable of separating antibodies with specific sugar structures (nonfucosylated) that are more potent against viruses and cancer. The Glycap-3A resin has been bought and used by more than half of the largest pharmaceutical companies.

Zepteon's Glycap-3A chromatography resin can be used to obtain the most potent glycoforms of hyperimmune antiviral IVIG or to make biosimilar antibodies with targeted nonfucose levels (Pace et. al, Biotech Prog, June 2016; btpr.2300).

In addition, Zepteon is the lowest cost supplier of the protein receptor FcgammaRIIIa.